Inclusion of growth factors
KytoGEL including fibroblast growth factor (FGF) enables to accelerate refractory wound healing of the diabetic mice.

• Refractory trauma of diabetic mice was treated with KytoGEL including FGF-2.
• FGF which was released following biodegradation of KytoGEL accelerates
• IIIIneovascularization leading to wound healing.
• Inclusion with KytoGEL enables to suppress the deactivation of growth factors.
• BBBBBBBBBBBBiomaterials 2004;26:3277-3284.
• BBBBBBBBBBBWound Rep Reg 2005; 13: 390-397.

Inclusion of chemotherapeutics
KytoGEL including Paclitaxel inhibited the expansion of model tumor which was established at mouse back.

• KytoGel including Paclitaxel (Pac) was subcutaneously injected into mouse back
• IIIIestablishing model tumor with B-16 melanoma, and then subjected to
• IIIIUV irradiation.
• KytoGel including Pac suppressed angiogenesis of the model tumor.
• KytoGel including Pac inhibited expansion of tumor.

(Journal of Controlled Release 2005; 110: 390-397)

• Topically stayed-drug delivery will reduce applied dose of drugs, and then suppress a IIIIrisk of side effect.
• KytoGel varies a use of drugs and elevates worth of the generics.

Hemostat
Endoscope
Wound care