Surgical hemostat
Effective hemostasis was observed at a bleeding model using heparinized rats.
- Liver of heparinized rats were mechanically incised and penetrated with a dermal IIIIpunch. A piece of the sponge was soaked in aqueous KytoGEL, immediately inserted IIIIinto the wound, and then irradiated to stop the bleeding.
- It was revealed that hemostatic ability of KytoGEL was superior to that of the leading IIIIhemostat containing coagulant factor.
- Artif Organs. 2010 Apr;34(4):342-7.
External preparation
Urgent hemostasis for a massive bleeding model using rats
(Time requirement for hemostasis)
- CELOX, HemCon, or QuikClot is adopted by military forces.
- CELOX:Chitosan powder containing an organic acid and surfactant
- HemCon:Chitosan-added bandage
- QuikClot: Promotion of clotting based on blood condensation using kaolinite
- (Acad Emerg Med. 2008 Jan;15(1):74-81.)
- A complex injury was created in the swine’s right groin to produce uncontrolled
- IIIIhemorrhage. After primary hemostasis, the percentage of rebleeding and survival
- IIIIwere examined.
(Acad Emerg Med. 2008 Jan;15(1):74-81.)
- Hemostasis of the bleeding at heparinized rat groin involving simultaneous resection IIIIof artery and vein.
Time requirement for hemostasis | |
CELOX powder | Complex powder of KytoGEL and other glucide |
Within 7 minutes | Within 4 minutes |
In basic study, it was revealed that KytoGEL had been superior hemostat in terms of hemostatic time and blood loss .