Japanese
Surgical hemostat
Effective hemostasis was observed at a bleeding model using heparinized rats.
Liver of heparinized rats were mechanically incised and penetrated with a dermal IIIIpunch. A piece of the sponge was soaked in aqueous KytoGEL, immediately inserted IIIIinto the wound, and then irradiated to stop the bleeding.
It was revealed that hemostatic ability of KytoGEL was superior to that of the leading IIIIhemostat containing coagulant factor. - Artif Organs. 2010 Apr;34(4):342-7.
External preparation
Urgent hemostasis for a massive bleeding model using rats
(Time requirement for hemostasis)
CELOX, HemCon, or QuikClot is adopted by military forces.
- CELOX：Chitosan powder containing an organic acid and surfactant
- HemCon：Chitosan-added bandage
- QuikClot: Promotion of clotting based on blood condensation using kaolinite
- (Acad Emerg Med. 2008 Jan;15(1):74-81.)
A complex injury was created in the swine’s right groin to produce uncontrolled- IIIIhemorrhage. After primary hemostasis, the percentage of rebleeding and survival
- IIIIwere examined.
(Acad Emerg Med. 2008 Jan;15(1):74-81.)
Hemostasis of the bleeding at heparinized rat groin involving simultaneous resection IIIIof artery and vein.
| Time requirement for hemostasis | |
| CELOX powder | Complex powder of KytoGEL and other glucide |
| Within 7 minutes | Within 4 minutes |
In basic study, it was revealed that KytoGEL had been superior hemostat in terms of hemostatic time and blood loss .
Topical DDS
Endoscope
Wound care
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Hemostasis
Topical DDS
Endoscope
Wound care
